Endocrine Abstracts

Introduction: Hypoglycemia is an uncommon complaint among non diabetic patients. The aim of this study was to determine the role of fast test in the diagnostic approach to hypoglycemia.Patients and methods: It was a retrospective study, including 40 patients admitted in the endocrinology department from 2001 to 2015 for hypoglycemia signs. We collected clinical and biologic data, fast test results and final diagnosis of hypoglycemia.<p class="abstext...

Introduction: Atrial fibrillation (AF) occurs in up to 15% of patients with hyperthyroidism. Although hyperthyroidism is usually regarded as a reversible cause of AF, spontaneous sinus conversion occurs in only 2/3 of patients upon the normalization of T4 levels. The aim of this study was to identify factors associated with persistent atrial fibrillation after restoration of euthyroid state.Methods: We conducted a retrospective study of 13 years. Twenty ...

Bakground: Thyroid-lobectomy is a frequent procedure performed in patients with a variety of thyroid conditions.The aim of this study is to determine the prevalence of post-operative hypothyroidism and the risk factors of hypothyroidism in patients undergoing thyroid-lobectomy.Patients and methods: We retrospectively reviewed patients who underwent a thyroid lobectomy for benign disease from january 2000 to 2014. Patients with known hypothyroidism before...

Introduction: Hypopituitarism is a known cause of bone mineral loss. Our study aimed to evaluate the frequency of osteopenia and osteoporosis in patients with Sheehan’s syndrome and to evaluate its management.Subjects and methods: It is a retrospective longitudinal study concerning 60 cases of Sheehan’s syndrome that have had a bone mineral density measurement. The parameters of osteodensitometry, the received treatment and the follow up data w...

Introduction: Steroid 11β-hydroxylase deficiency (11-OHD) is the second most common causeof congenital adrenal hyperplasia (CAH),characterized by the overproduction of adrenal androgens and deoxycorticosterone (DOC).It usually presents with virilization of the female fetus, precocious puberty in male infants and hypertension with or without hypokalemia in both genders. Because of high levels of mineralocorticoids, patients rarely present with salt wasting (SW). We herein ...

Introduction: Severe hypercalcemia is a life-threatening condition which should be managed urgently. Its pharmacological treatment consists of intravenous saline hydration, loop diuretic and intravenous administration of bisphosphonates. However, data evaluating these treatments are very limited.The aim of this study was to assess the efficiency of saline hydration, furosemide, and bisphosphonates in the management of severe hypercalcemia secondary to a ...

Introduction: Primary adrenal insufficiency is a classically rare but potentially serious disease due to the risk of acute adrenal crisis. Although autoimmune origin is the first etiology in adults, genetic causes are most common in children.Herein, we reporta case of coexisting hypogonadotropic hypogonadism and growth hormone (GH) deficiency in a patient with Addison’s disease.Observation: A 15-year-old boy was referred to o...

Introduction: Short stature is a common feature in Turner syndrome. It is caused by haplo-insufficiency of the SHOX gene. Growth hormone deficiency does not occur in this disorder as confirmed by the normal GH response to stimulation tests. However, few cases of coexisting GH deficiency and Turner syndrome have been reported. We herein describe two cases of GH deficiency in patient with Turner syndrome.Observation 1: A 20-year-old patient was referred fo...

Introduction: Hyponatremia represents a frequent electrolyte disorder. It is defined as a serum sodium level below 135 mmol/L and it is severe when serum level is below 125 mmol/l. Endocrine disorders including adrenal deficiency and hypothyroidism are uncommon causes of hyponatremia. Secondary adrenal insufficiency is related with hyponatremia through increased ADH secretion.Herein, we report a case of severe hyponatremia revealing hypopituitarism.<...

Introduction: Adrenocortical carcinoma (ACC) is a rare aggressive endocrine neoplasm. It’s a heterogeneous malignant tumor with incompletely understood pathogenesis and poor prognosis. The aim of our study was to assess clinical and paraclinical characteristics of ACC and to determine its outcome.Methods: In a retrospective and descriptive study, we included patients with adrenocortical carcinoma confirmed with histopathological examination. Clinic...